Clinical Research


Our Clinical Research Center is under the direction of Dr. Rex Force. The center is actively engaged in cutting-edge clinical research and has taken part in several landmark National Institute of Health trials that have significantly influenced how doctors treat high blood pressure, diabetes, and congestive heart failure. Ongoing research studies will evaluate how best to prevent heart attacks and stroke. Following are some of our current clinical trials, articles published on our research, and information on our current research staff:

Clinical Trials

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EXSCEL

The purpose of this study is to assess the effectiveness and safety of a once weekly dose of exenatide injection on type 2 diabetes, as well as its effect on cardiovascular disease in individuals older than 18 years of age.

Exenatide or placebo will be given subcutaneously once weekly. Exenatide has been approved by the U.S. Food and Drug Administration (FDA) when given twice per day. Recently, exenatide once weekly was approved by the FDA.

This study is intended for patients who are having difficulty controlling their blood sugars and already have cardiovascular disease.

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ELIXA

ELIXA is a clinical trial being done to see if lowering the blood sugar with an experimental anti-diabetes medication will prevent future "cardiovascular events" such as heart attacks and strokes in people with type 2 diabetes who have already experienced a cardiovascular event. The experimental medication, called lixisenatide, will be compared to a placebo. Either lixisenatide or placebo will be injected once a day using an injection "pen."

This study is for people who have both diabetes and heart disease, and who have recently been in the hospital for a cardiovascular event such as heart attack or unstable angina. In total, 6,000 people like you are being enrolled in approximately 50 countries.

People who enroll in ELIXA will receive all their study-related medical care and diabetes testing supplies for free. Also, if you join you will get diet and exercise counseling. Maybe most important, you will be seen by an expert doctor who will closely watch your diabetes and heart disease.

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TECOS

What is the reason for TECOS?  We know that control of blood sugar in diabetes will reduce the risk of damage in the eyes, kidneys, and nerves. There are now many types of medications available to lower blood sugars and help prevent these complications; however, it is possible that these medications may affect the cardiovascular system in different ways.

Articles

Research Staff

Rex Force, Pharm D

Rex Force, Pharm D

Director of Grants, Research and Information Systems

ISU Clinical Research Center
Phone:  208-282-4176
Fax:  208-282-5701
Ron Solbrig, MD

Ron Solbrig, MD

Medical Investigator

ISU Clinical Research Center
Phone:  208-282-2330
Fax:  208-282-5701
Eliza Borzadek, Pharm D

Eliza Borzadek, Pharm D

Research Professor

ISU Clinical Research Center
Phone:  208-282-3413
Fax:  208-282-5701
John Holmes, Pharm D

John Holmes, Pharm D

Research Professor

ISU Clinical Research Center
Phone:  208-282-5391
Fax:  208-282-5701
Loni Chacon, LPN

Loni Chacon, LPN

Study Coordinator

ISU Clinical Research Center
Phone:  208-282-4176
Fax:  208-282-5701